In that sense, Upside Down is a variation on two futurist fantasies written and directed by Andrew Niccol: the 1997 Gattaca, in which a genetically modified race lords it over the unimproved humans; and the 2011 In Time, where the Haves have cornered the lifespan market and everyone else dies at the age of 25.
Adult sci-fi fans who want something more than rockets and rayguns — the sort who adored "Gattaca," and "Inception" and can tell you how every Philip K. Dick adaptation since "Blade Runner" has gotten him wrong — would be this film's natural audience, if it were done well.